TCDB is operated by the Saier Lab Bioinformatics Group
TRANSPORTERS FROM HUMANS:
Transporter Information:
Name: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1
Symbol: ATP5F1
TC: 3.A.2.1.3
Enzyme: 3.6.1.34
Locations: reserved
GenBank: X60221
Swiss-Prot: P24539
Accession Number: NM_001688
GDBGDB:137189
LocusLink515
OMIM603270
PubMed (1831354): Higuti T, Tsurumi C, Osaka F, Kawamura Y, Tsujita H, Yoshihara Y, Tani I,Tanaka K, Ichihara A. Molecular cloning of cDNA for the import precursor of human subunit B ofH(+)-ATP synthase in mitochondria.Biochem Biophys Res Commun. 1991 Aug 15;178(3):1014-20. PMID: 1831354 [PubMed - indexed for MEDLINE]

The nucleotide sequence of the import precursor of subunit b of human H(+)-ATP synthase has been determined from a recombinant cDNA clone isolated by screening a human kidney cDNA library with a cDNA for rat subunit b as a probe. The sequence was composed of 1,134 nucleotides including a coding region for the import precursor of subunit b and noncoding regions on the 5'- and 3'-sides. The import precursor of subunit b and its mature polypeptide deduced from the open reading frame were found to consist of 256 and 214 amino acid residues with molecular weights of 28,893 and 24,610, respectively. The presequence of 42 amino acids could be the import signal peptide for directing the protein into the mitochondrial matrix.