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2.A.6.2.14
SmeVWX MDR efflux pump. Drugs include chloramphenicol, quinolones, tetracyclines and aminoglycosides, but not β-lactams and erythromycin (Chen et al., 2011).

Accession Number:B2FLY4
Protein Name:Putative drug resistance membrane fusion protein
Length:1056
Molecular Weight:113539.00
Species:Stenotrophomonas maltophilia (strain K279a) [522373]
Number of TMSs:12
Substrate Chloramphenicol, Quinolones, tetracycline, Aminoglycosides

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDFSRFFIDR PIFAAVLSIV IFAAGLITIP ILPISEYPEV VPPSVVVRTV YPGANPKVIA 
61:	ETVATPLEEA INGVEGMMYL KSVAGSDGVL QMTVTFRPGT DPDAAAVKVQ NRVAQAQARL 
121:	PEDVRRQGVT TQKQSPTFLM VVHLTSPQGK YDTLYLRNYA RLHVKDALAR IPGVGDAQIF 
181:	GGGDYAMRAW LDPDKVASRG LTASDVVRAM REQNVQVSAG QLGAEPLPDS KFLTLINAQG 
241:	RLKTEKEFGD IVLKSGTDGE IVRLSDVARL ELGAGDYTLR SQLDGKNAVG IGIFQSPGAN 
301:	ALEIRDQVIS TMDEMQKTMP ADVKYEAVYD TTIFVRDSIK AVVSTLLEAI ALVVLVVILF 
361:	LQTWRASIIP LIAVPVSVVG TFAALYLLGF SINTLSLFGL VLAIGIVVDD AIVVVENVER 
421:	NIEEGLSPTA AAHQAMREVS GPIVAIALVL CAVFVPMAFL SGVTGQFYKQ FAVTIAISTV 
481:	ISAINSLTLS PALAARLLKA HGAPKDGPSR LIDRLFGWVF RPFNRFFKSS SEKYERGVAR 
541:	ILGRRGAVFV VYAILLVGTG VIFKLVPPGF IPTQDKLYLI AGVKLPEGSS IARTDEMLRK 
601:	VAKIAQETDG VAHTISFPGL NALQFTNTPN TGVAFIPLKP FAERHGRTAA QINAEINQKI 
661:	AGLQEGFAFA MMPPPILGLG NGNGYQMFIE DRGNLGYGAL QNAVQAMQGT VAQTPGMAFP 
721:	ISSYQANVPQ LDAEVDRVKA KAQGVQLTEL FDTLQTYLGS AYVNDFNQFG RTWQVIAQAD 
781:	GPFRETVEDI GKLRTRNDRG EMVPIGSMVT IKQTFGPDPV LRFNGYPAAD LAGEADPRLL 
841:	SSAEAMTKLT EIAGKVLPVG MTTEWTDLSY QQATQGKAAF IVFPVAIMLA FLVLAALYES 
901:	WSLPLAVILI VPMTLLSALF GVWLTGGDNN VFVQVGLVVL MGLACKNAIL IVEFARELEM 
961:	GGKGIVEAAL EACRLRLRPI VMTSIAFIAG TVPLVLSHGA GAEVRSVTGI TVFAGMLGVT 
1021:	LFGLFLTPVF YVALRKFVTR NGGGQLVQHG EPTIHH