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2.A.6.2.43
Multidrug resistance pump, SmeJK. Shown to export teracycline, minocycline, ciprofloxacin and levofloxacin (Gould et al., 2012).

Accession Number:I0KTJ0
Protein Name:Acriflavin resistance plasma membrane protein
Length:1077
Molecular Weight:115418.00
Species:Stenotrophomonas maltophilia D457 [1163399]
Number of TMSs:12
Substrate tetracycline, Monocycline, Ciprofloxacin, Levofloxacin

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGFSTIFIRR PIATSLLMAG LLLLGILGYR KLPVSALPEI DAPSLVVTTQ YPGANATTMA 
61:	SLVTTPLERQ FGQISGLELM TSDSSAGLST IILQFSMDRD IDIAAQDVQA AIRQATLPSS 
121:	LPYQPVYNRV NPADAAIVTL KLTSDTRPLR DVNNYADSIL AQRLSQVQGV GLVSIAGNVR 
181:	PAVRIQVNPA QLSNMGLTLE QLRSALTQAN VNAPKGSLNG KTQSYSIGTN DQLASAAEYR 
241:	DTIISYKNGR PVRLSDVAEV IDGVENDQLA AWADGKPAVL LEVRRQPGAN IVQTVERIRA 
301:	ILPQLQGVLP ADVHLEIFND RTETIRASVH EVQFTLILTI GLVVAVIFVF LRRLWATIIP 
361:	SVAVPLSLAG TFAVMAFAGM SLDNLSLMAL VVATGFVVDD AIVMIENIVR YIEQGKSGKE 
421:	AAEIGARQIG FTVLSLTVSL VAVFLPLLLM PGVTGRLFHE FAWVLSIAVV LSMLISLTLT 
481:	PMMCAYLLKP DALPEGEDAH ERAAAAGKQN LWTRTVGLYE HSLDWVLDHQ RLTLAVAGGA 
541:	LVLTVLLYVL IPKGLLPEQD TGLITGVVQA DQNIAFPQME QRTKQVAEAL RHDPDVTGVS 
601:	AFIGAGSMNP TLNQGQLSIV LKERSQRDGL EQILPRLQKA VAGIPGVALY LKPVQDVTLD 
661:	TRVAATEYQY SLSDVDSATV ATQATRLTEA LRKRPELADV DNNLSNQGRA LELNIDRDKA 
721:	SVLGVPMQTI DDTLYDAFGQ RQISTIFTEL NQYRVVLEVA PEFRTSTALM EQLAVASNGA 
781:	GALTGTNATS FGQVTSSNSS TATGIGAQNT GITVGAGNII PLSALAEGKV SSAPLVVSHQ 
841:	QQLPAVTVSF NVAPGYSLSE AVRAIQETKD SLDMPTHLHA EFIGKAAEFT GSQTDVVWLL 
901:	LASLVVIYIV LGVLYESYIH PITIISTLPP AGVGALLALM LCGLSLSVDG IVGIVLLIGI 
961:	VKKNGIMMVD FAIEARRAGA NAHEAIRRAC LLRFRPIMMT TAAAMLGALP LALGTGIGSE 
1021:	LRRPLGIAIV GGLLLSQLVT LYTTPVIYLY MERFSEWLAR RREQRALRDG SLQEPQA