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2.A.6.2.43
Multidrug resistance pump, SmeJK. Shown to export teracycline, minocycline, ciprofloxacin and levofloxacin (Gould et al., 2012).

Accession Number:I0KTJ1
Protein Name:Acriflavin resistance plasma membrane protein
Length:1040
Molecular Weight:111644.00
Species:Stenotrophomonas maltophilia D457 [1163399]
Number of TMSs:12
Substrate tetracycline, Monocycline, Ciprofloxacin, Levofloxacin

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNLSGPFIRR PIGTALLAIG LFMVGLICYL RLGVSALPNI EIPVIFVHAS QSGADAATMA 
61:	STVTAPLERH LGQLPGIDRM RSSSSEGSSL VFMIFQSGHN IDSAALDVQT AINSAQADLP 
121:	SGMGSPMYQK ANPNDDPVIA IALTSQTQSA DELYNVADSL LAQRIRQISG VASVDIAGAS 
181:	TPAVRVDVNL RLMNALGLTA DDLRNAVRAA NVTSPTGFLS DGNTTTAIIA NDSVARAADF 
241:	ADLVVKTQGD GRVIRLKDIA NVYDGQQDAY QAAWFDHKPA VVMYVFTRAG ANIVETVDRV 
301:	KAQIPTLRDY LQPGTTMTPY FDRTPTIRSS LHEVQITLLI SLAMVVLTMA LFLRRLAPTL 
361:	IAAVTVPLSL AGAALVMYVM GFTLNNLSLL ALVIAIGFVV DDAIVVIENI MRHLDEGMPR 
421:	MQAALTGARE IGFTIVSITA SLVAVFIPLL FASGMMGAFF REFTVTLVAA IVVSMIVSLT 
481:	LTPALCSRFL SAHDHSAPPS RFGRWLDAGH ERMLRIYTVF LDFSLRHALL LSLTPLILIG 
541:	VTIFLFGAVK KGAFPPQDTG LIWGRANSSA TVSFEDMVAR QRRITDMLMA DPAVKTVGVR 
601:	LGSGRQGSSA QFNIELKSRS DGRRETTAHA LARLSAKADR YPDLQLRLRA IQDLPSNDGG 
661:	GSSQGAQYRI SLQGNDLAAL QEWLPKLQAK LKKNPKLRDV GTDVDNAGLR QNIQIDRAKA 
721:	ARLGITVGAI DGALYGAFGQ RQISTIYSDI NQYSVVVNAL PSQTATPAAL DEVYVRARNG 
781:	DMVPITAVAT QMPGLAPSQI THENQYTTMD LSYNLAPNVS MGEAKAIIDA TVAGMRMPGD 
841:	IRLADDAGFG FNSDPSDMLI LVFAAILTVY LVLGMLYESL IHPVTILSTL PAAGVGALLA 
901:	LFGTNTELSV ISMIALVLLI GIVKKNAIMM IDFALVAQRE HGLAPRDAAR EASIVRFRPI 
961:	MMTTMVAILA AVPLAIGLGE GSELRRPLGI AMIGGLLFSQ SLTLLSTPAL YVIFSCLAER 
1021:	WRARRARRRE AKLLKRAQRA