TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.6.1.14
CznABC Cd2+, Zn2+, Ni2+ resistance efflux pump. Required for urea modulation and gastric colonization (Stähler et al., 2006).

Accession Number:O25622
Protein Name:Cation efflux system protein (CzcA)
Length:1020
Molecular Weight:111323.00
Species:Helicobacter pylori (strain ATCC 700392 / 26695) [85962]
Number of TMSs:12
Substrate Cd2+, Zn2+, Ni2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MMLASIIEFS LRQRVIVIVG AILILFFGTY SFINTPVDAF PDISPTQVKI ILKLPGSSPE 
61:	EMENNIVRPL ELELLGLKGQ KSLRSVSKYS ISDITIDFDD SVDIYLARNI VNERLSSVMK 
121:	DLPVGVEGGM APIVTPLSDI FMFTIDGNIT EIEKRQLLDF VIRPQLRMIS GVADVNSIGG 
181:	FSRAFVIVPD FNDMARLGVS ISDLESAVRV NLRNSGAGRV DRDGETFLVK IQTASLSLED 
241:	IGKITVSTNL GHLHIKDFAK VISQSRTRLG FVTKDGVGET TEGLVLSLKD ANTKEIITQV 
301:	YQKLEELKPF LPNGVSINVF YDRSEFTQKA IATVSKTLIE AVVLIIITLF LFLGNLRASV 
361:	AVGVILPLSL SVAFIFIKFS DLTLNLMSLG GLVIAIGMLI DSAVVVVENA FEKLSANTKT 
421:	TKLHAIYRSC KEIAVSVVSG VVIIIVFFVP ILTLQGLEGK MFRPLAQSIV YALLGTLVLS 
481:	ITIIPVVSSL VLKATPHSET FLTRFLNRIY APLLEFFVHN PKKVILGAFV FLIASLSLFP 
541:	FVGKNFMPVL DEGDVVLSVE TTPSISLDQS RDLMLNIESA IKKHVKEVKS IVARTGSDEL 
601:	GLDLGGLNQT DTFISFIPKK EWSVKTKDEL LEKIMDSLKD FKGINFSFTQ PIEMRISEML 
661:	TGVRGDLAVK IFGDGISELN ELSFQIAQAL KGIKGSSEVL TTLNEGVNYL YVTPNKESMA 
721:	DVGITSDEFS KFLKSALEGL VVDVIPTGIS RTPVMIRQES DFASSITKIK SLALTSKYGV 
781:	LVPITSIAKI EEVDGPVSVV RENSMRMSVV RSNVVGRDLK SFVEEAKKVI AQNIKLPPSY 
841:	YITYGGQFEN QQRANKRLST VIPLSILAIF FILFFTFKSI PLALLILLNI PFAVTGGLIA 
901:	LFAVGEYISV PASVGFIALF GIAVLNGVVM IGYFKELLLQ GKSVEECVLL GAKRRLRPVL 
961:	MTACIAGLGL LPLLFSHSVG SEVQKPLAIV VLGGLVTSSA LTLLLLPPMF MLIAKKIKIV