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3.A.1.14.21
The heme uptake porter, PhuTUV (transports one heme per reaction cycle) (Mattle et al., 2010).

Accession Number:O68877
Protein Name:Hemin import ATP-binding protein HmuV
Length:255
Molecular Weight:27525.00
Species:Pseudomonas aeruginosa [287]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate Heme

Cross database links:

HEGENOM: HBG758042
Entrez Gene ID: 881536   
Pfam: PF00005   
KEGG: pae:PA4706   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0005215 F:transporter activity

References (2)

[1] “Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.”  Ochsner U.A.et.al.   8633080
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLRVENLSIR RGGKTVLEGL ELELRPGEML GVLGPNGAGK STLLGALCGE LEPAEGLVLL 
61:	DERGLDDWPG VARAQRLAVL PQSSSLGFAF PVEAVVGFGR LPHSSGRERD VQIVAEALAA 
121:	ADASHLAGRS YLALSGGERQ RVHLARVLAQ LWPGEPGQVL LLDEPTSALD PLHQHTTLQA 
181:	VHDFARRGAS VLVILHDLNL AARYCDRLLL LQNGRPHLLG TPEEVLRPEP LRAVFGLEVL 
241:	VQRHPERGHP LIVAR