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3.A.1.15.3
Zinc (Zn2+) porter, AdcABC/AII

Accession Number:P0A2U6
Protein Name:AdcC aka SP2171
Length:234
Molecular Weight:26542.00
Species:Streptococcus pneumoniae [1313]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_346585.1   
Entrez Gene ID: 930195   
Pfam: PF00005   
KEGG: spn:SP_2171   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0030420 P:establishment of competence for transformation
GO:0006829 P:zinc ion transport

References (2)

[1] “Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.”  Tettelin H.et.al.   11463916
[2] “Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases.”  Dintilhac A.et.al.   9379902

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MRYITVEDLS FYYDKEPVLE HINYCVDSGE FVTLTGENGA AKTTLIKASL GILQPRIGKV 
61:	AISKTNTQGK KLRIAYLPQQ IASFNAGFPS TVYEFVKSGR YPRKGWFRRL NAHDEEHIKA 
121:	SLDSVGMWEH RDKRLGSLSG GQKQRAVIAR MFASDPDVFI LDEPTTGMDA GSKNEFYELM 
181:	HHSAHHHGKA VLMITHDPEE VKDYADRNIH LVRNQDSPWR CFNVHENGQE VGHA