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3.A.1.112.3
Bacteriocin (lactococcin) exporter. 

Accession Number:P0A3G5
Protein Name:Lactococcin A secretion protein lcnD
Length:474
Molecular Weight:52538.00
Species:Lactococcus lactis subsp. lactis (Streptococcus lactis) [1360]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Single-pass type II membrane protein2
Substrate Lactococcin

Cross database links:

Pfam: PF00529   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008565 F:protein transporter activity
GO:0043213 P:bacteriocin transport
GO:0009306 P:protein secretion

References (2)

[1] “Molecular analyses of the lactococcin A gene cluster from Lactococcus lactis subsp. lactis biovar diacetylactis WM4.”  Stoddard G.W.et.al.   1622271
[2] “Topology of LcnD, a protein implicated in the transport of bacteriocins from Lactococcus lactis.”  Franke C.M.et.al.   8626308

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MFDKKLLESS ELYDKRYRNF STLIILPLFI LLVGGVIFTF FAHKELTVIS TGSIEPTKIV 
61:	AKIQSTNANP IIENNLKEGE AVKENSLLLK YNGTPEQTQL SELLTQKKQA LDKKVQLDLL 
121:	QRSLTNEKNE FPTADSFGYE KSFENYEAQV KSLEATIQKS NQAVEDQNKS TESQKQAIQN 
181:	QVATLQQAIQ NYSEIENAVS SGGGVSQDNP YLSQYNSYQA QQATLEADLK NQKNPDETAK 
241:	QAAKSQEESL KSQFLSGLAS SKDSLKSQIQ SFNVQESSLT GSNAYDNSQS SQILTLKSQA 
301:	LSASNKEMTD LNSTLTDLET KISLQKQDDQ YSQVFAEQAG VLHVLPDILG MKKIPIGTPI 
361:	AEIYPLLKSE TQVNLTSYIP STQISGMKVG QKVRFTVQQN LPQPEILTGI INQIDSAPTA 
421:	FKEGNAYKVS ATTTINAKDL PNIRYGLQGK TVTIIGKKTY FNYFLDKIMG RGNQ