TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.6.1
Sulfate/thiosulfate porter

Accession Number:P0AEB0
Protein Name:Sulfate transport system permease protein CysW aka B2423
Length:291
Molecular Weight:32538.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Sulfate, Thiosulfate

Cross database links:

Genevestigator: P0AEB0
EchoBASE: EB0195
EcoGene: EG10198
eggNOG: COG4208
HEGENOM: HBG685300
RefSeq: AP_003017.1    YP_026168.2   
Entrez Gene ID: 2847743   
Pfam: PF00528   
BioCyc: EcoCyc:CYSW-MONOMER    ECOL168927:B2423-MONOMER   
KEGG: ecj:JW2416    eco:b2423   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015116 F:sulfate transmembrane transporter activity
GO:0015563 F:uptake transmembrane transporter activity
GO:0008272 P:sulfate transport

References (5)

[1] “Sulfate and thiosulfate transport in Escherichia coli K-12: nucleotide sequence and expression of the cysTWAM gene cluster.”  Sirko A.et.al.   2188958
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAEVTQLKRY DARPINWGKW FLIGIGMLVS AFILLVPMIY IFVQAFSKGL MPVLQNLADP 
61:	DMLHAIWLTV MIALIAVPVN LVFGILLAWL VTRFNFPGRQ LLLTLLDIPF AVSPVVAGLV 
121:	YLLFYGSNGP LGGWLDEHNL QIMFSWPGMV LVTIFVTCPF VVRELVPVML SQGSQEDEAA 
181:	ILLGASGWQM FRRVTLPNIR WALLYGVVLT NARAIGEFGA VSVVSGSIRG ETLSLPLQIE 
241:	LLEQDYNTVG SFTAAALLTL MAIITLFLKS MLQWRLENQE KRAQQEEHHE H