TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.1.3
Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P (Yang et al. 2009; Wuttge et al. 2012).  UgpB (the receptor) binds glycerol 3-P with high affinity, but not glycerol 2-P (Wuttge et al. 2012).  UgpB (the receptor) binds glycerol 3-P with high affinity, but not glycerol 2-P (Wuttge et al. 2012).

Accession Number:P0AG80
Protein Name:sn-glycerol-3-phosphate-binding periplasmic protein UgpB aka B3453
Length:438
Molecular Weight:48449.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate Glycerol-phosphate

Cross database links:

Genevestigator: P0AG80
EchoBASE: EB1040
EcoGene: EG11047
eggNOG: COG1653
HEGENOM: HBG313575
DIP: DIP-35942N
RefSeq: AP_004339.1    NP_417910.1   
Entrez Gene ID: 947962   
Pfam: PF01547   
BioCyc: EcoCyc:UGPB-MONOMER    ECOL168927:B3453-MONOMER   
KEGG: ecj:JW3418    eco:b3453   

Gene Ontology

GO:0042597 C:periplasmic space
GO:0005515 F:protein binding
GO:0005215 F:transporter activity
GO:0070811 P:glycerol-2-phosphate transport
GO:0015794 P:glycerol-3-phosphate transport

References (4)

[1] “Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system.”  Overduin P.et.al.   3062310
[2] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
Structure:
4AQ4     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKPLHYTASA LALGLALMGN AQAVTTIPFW HSMEGELGKE VDSLAQRFNA ENPDYKIVPT 
61:	YKGNYEQNLS AGIAAFRTGN APAILQVYEV GTATMMASKA IKPVYDVFKE AGIQFDESQF 
121:	VPTVSGYYSD SKTGHLLSQP FNSSTPVLYY NKDAFKKAGL DPEQPPKTWQ DLADYAAKLK 
181:	ASGMKCGYAS GWQGWIQLEN FSAWNGLPFA SKNNGFDGTD AVLEFNKPEQ VKHIAMLEEM 
241:	NKKGDFSYVG RKDESTEKFY NGDCAMTTAS SGSLANIREY AKFNYGVGMM PYDADAKDAP 
301:	QNAIIGGASL WVMQGKDKET YTGVAKFLDF LAKPENAAEW HQKTGYLPIT KAAYDLTREQ 
361:	GFYEKNPGAD TATRQMLNKP PLPFTKGLRL GNMPQIRVIV DEELESVWTG KKTPQQALDT 
421:	AVERGNQLLR RFEKSTKS