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3.A.6.2.1
Flagellar protein export system.  Infrequent ATP hydrolysis by the FliI6FliJ ring is sufficient for gate activation, allowing processive translocation of export flagellar protein substrates for efficient flagellar assembly (Minamino et al. 2014). FliO has been identified as a flagellar basal body chaparone protein (Fabiani et al. 2017). The flagellar protein export apparatus switches its substrate specificity when hook length has reached approximately 55 nm, and the hydrophilic C-terminal domain of FlhB is involved in this switching process (Inoue et al. 2019).

Accession Number:P15934
Protein Name:FliH aka FLA BIII aka FLA AII.3 aka STM1971
Length:235
Molecular Weight:25811.00
Species:Salmonella typhimurium [90371]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate Flagellar proteins

Cross database links:

HEGENOM: HBG504712
RefSeq: NP_460924.1   
Entrez Gene ID: 1253492   
Pfam: PF02108   
BioCyc: STYP99287:STM1971-MONOMER   
KEGG: stm:STM1971   

Gene Ontology

GO:0009288 C:bacterial-type flagellum
GO:0005737 C:cytoplasm
GO:0003774 F:motor activity
GO:0001539 P:ciliary or flagellar motility
GO:0043064 P:flagellum organization
GO:0015031 P:protein transport

References (3)

[1] “Salmonella typhimurium mutants defective in flagellar filament regrowth and sequence similarity of FliI to F0F1, vacuolar, and archaebacterial ATPase subunits.”  Vogler A.P.et.al.   1646201
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[3] “Flagellar switch of Salmonella typhimurium: gene sequences and deduced protein sequences.”  Kihara M.et.al.   2656645

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSNELPWQVW TPDDLAPPPE TFVPVEADNV TLTEDTPEPE LTAEQQLEQE LAQLKIQAHE 
61:	QGYNAGLAEG RQKGHAQGYQ EGLAQGLEQG QAQAQTQQAP IHARMQQLVS EFQNTLDALD 
121:	SVIASRLMQM ALEAARQVIG QTPAVDNSAL IKQIQQLLQQ EPLFSGKPQL RVHPDDLQRV 
181:	EEMLGATLSL HGWRLRGDPT LHHGGCKVSA DEGDLDASVA TRWQELCRLA APGVL