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3.A.1.6.1
Sulfate/thiosulfate porter

Accession Number:P16676
Protein Name:CysA aka B2422
Length:365
Molecular Weight:41059.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate Sulfate, Thiosulfate

Cross database links:

Genevestigator: P16676
EchoBASE: EB0180
EcoGene: EG10183
eggNOG: COG1118
HEGENOM: HBG758042
DIP: DIP-9373N
RefSeq: AP_003016.1    NP_416917.1   
Entrez Gene ID: 946889   
Pfam: PF00005   
BioCyc: EcoCyc:CYSA-MONOMER    ECOL168927:B2422-MONOMER   
KEGG: ecj:JW2415    eco:b2422   

Gene Ontology

GO:0043190 C:ATP-binding cassette (ABC) transporter complex
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015419 F:sulfate transmembrane-transporting ATPase a...
GO:0008272 P:sulfate transport

References (5)

[1] “Sulfate and thiosulfate transport in Escherichia coli K-12: nucleotide sequence and expression of the cysTWAM gene cluster.”  Sirko A.et.al.   2188958
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Molybdate and regulation of mod (molybdate transport), fdhF, and hyc (formate hydrogenlyase) operons in Escherichia coli.”  Rosentel J.K.et.al.   7665461

External Searches:

  • Search: DB with
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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSIEIANIKK SFGRTQVLND ISLDIPSGQM VALLGPSGSG KTTLLRIIAG LEHQTSGHIR 
61:	FHGTDVSRLH ARDRKVGFVF QHYALFRHMT VFDNIAFGLT VLPRRERPNA AAIKAKVTKL 
121:	LEMVQLAHLA DRYPAQLSGG QKQRVALARA LAVEPQILLL DEPFGALDAQ VRKELRRWLR 
181:	QLHEELKFTS VFVTHDQEEA TEVADRVVVM SQGNIEQADA PDQVWREPAT RFVLEFMGEV 
241:	NRLQGTIRGG QFHVGAHRWP LGYTPAYQGP VDLFLRPWEV DISRRTSLDS PLPVQVLEAS 
301:	PKGHYTQLVV QPLGWYNEPL TVVMHGDDAP QRGERLFVGL QHARLYNGDE RIETRDEELA 
361:	LAQSA