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3.A.1.10.1
Ferric iron (Fe3+) porter, SfuABC (Angerer et al. 1990). These iron uptake systems have been reviewed (Angerer et al. 1992). Delepelaire 2019 reviewed structural and functional aspects of iron ABC transporters with emphasis on their substrate binding proteins.

Accession Number:P21409
Protein Name:SfuB aka FBPB
Length:527
Molecular Weight:56528.00
Species:Serratia marcescens [615]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fe3+

Cross database links:

Pfam: PF00528   
Drugbank: Drugbank Link   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006826 P:iron ion transport

References (1)

[1] “Nucleotide sequences of the sfuA, sfuB, and sfuC genes of Serratia marcescens suggest a periplasmic-binding-protein-dependent iron transport mechanism.”  Angerer A.et.al.   2404942

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSNLSTHAAQ TARRYSVVPR HPRPGAIVVV SAVLLSLLAL LPLGFVIGVA FETGWQTVKA 
61:	LVFRPRVAEL LLNTLLLVVL TLPICAVLGV ALAWLTERTT LPGRRLWAVL ATAPLAVPAF 
121:	VQSYAWISLV PSMHGLGAGV FISVLAYFPF IYLPAAAVLR RLDPGIEDVA TSLGSRPPAV 
181:	FFRVVLPQLK LAVCGGSLLI ALHLLAEYGL YAMIRFDTFT TAIFDQFQST FNGPAANMLA 
241:	GVLVLCCLGL LLLEAISRGR ARYARVGSGS ARSQTPRRLS PPLAALALLL PIALTALALG 
301:	VPFITLARWL WLGGFEVWRN AELWPALWQT LSLSAAGALL ITLCAIPMAW LSVRYPARLY 
361:	RVLEGCNYVT SSLPGIVVAL ALVTITIHSF RPIYQTEITL LLAYLLMFMP RALINLRAGI 
421:	AQAPVELENV ARSLGKSPAQ ALWSTTLRLA APGVAAGAAL VFLAIANELT ATLLLAPNGT 
481:	RTLATGFWAL TSEIDYVAAA PYALIMVALS LPLTWLLYSQ SKRTAGL