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3.A.1.10.1
Ferric iron (Fe3+) porter

Accession Number:P21409
Protein Name:SfuB aka FBPB
Length:527
Molecular Weight:56528.00
Species:Serratia marcescens [615]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fe3+

Cross database links:

Pfam: PF00528   
Drugbank: Drugbank Link   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006826 P:iron ion transport

References (1)

[1] “Nucleotide sequences of the sfuA, sfuB, and sfuC genes of Serratia marcescens suggest a periplasmic-binding-protein-dependent iron transport mechanism.”  Angerer A.et.al.   2404942

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSNLSTHAAQ TARRYSVVPR HPRPGAIVVV SAVLLSLLAL LPLGFVIGVA FETGWQTVKA 
61:	LVFRPRVAEL LLNTLLLVVL TLPICAVLGV ALAWLTERTT LPGRRLWAVL ATAPLAVPAF 
121:	VQSYAWISLV PSMHGLGAGV FISVLAYFPF IYLPAAAVLR RLDPGIEDVA TSLGSRPPAV 
181:	FFRVVLPQLK LAVCGGSLLI ALHLLAEYGL YAMIRFDTFT TAIFDQFQST FNGPAANMLA 
241:	GVLVLCCLGL LLLEAISRGR ARYARVGSGS ARSQTPRRLS PPLAALALLL PIALTALALG 
301:	VPFITLARWL WLGGFEVWRN AELWPALWQT LSLSAAGALL ITLCAIPMAW LSVRYPARLY 
361:	RVLEGCNYVT SSLPGIVVAL ALVTITIHSF RPIYQTEITL LLAYLLMFMP RALINLRAGI 
421:	AQAPVELENV ARSLGKSPAQ ALWSTTLRLA APGVAAGAAL VFLAIANELT ATLLLAPNGT 
481:	RTLATGFWAL TSEIDYVAAA PYALIMVALS LPLTWLLYSQ SKRTAGL