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3.A.6.2.1
Flagellar protein export system.  Infrequent ATP hydrolysis by the FliI6FliJ ring is sufficient for gate activation, allowing processive translocation of export flagellar protein substrates for efficient flagellar assembly (Minamino et al. 2014). FliO has been identified as a flagellar basal body chaparone protein (Fabiani et al. 2017). The flagellar protein export apparatus switches its substrate specificity when hook length has reached approximately 55 nm, and the hydrophilic C-terminal domain of FlhB is involved in this switching process (Inoue et al. 2019).

Accession Number:P26419
Protein Name:FliN aka MOTD aka FLAN aka STM1977
Length:137
Molecular Weight:14789.00
Species:Salmonella typhimurium [90371]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2 / Cytoplasmic side3
Substrate Flagellar proteins

Cross database links:

HEGENOM: HBG536886
RefSeq: NP_460930.1   
Entrez Gene ID: 1253498   
Pfam: PF01052   
BioCyc: STYP99287:STM1977-MONOMER   
KEGG: stm:STM1977   

Gene Ontology

GO:0009425 C:bacterial-type flagellum basal body
GO:0005886 C:plasma membrane
GO:0003774 F:motor activity
GO:0006935 P:chemotaxis
GO:0001539 P:ciliary or flagellar motility

References (3)

[1] “Flagellar switch of Salmonella typhimurium: gene sequences and deduced protein sequences.”  Kihara M.et.al.   2656645
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[3] “The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium: putative components for flagellar assembly.”  Ohnishi K.et.al.   9324257
Structure:
4YXB   4YXC     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDMNNPSDE NTGALDDLWA DALNEQKATT TKSAADAVFQ QLGGGDVSGA MQDIDLIMDI 
61:	PVKLTVELGR TRMTIKELLR LTQGSVVALD GLAGEPLDIL INGYLIAQGE VVVVADKYGV 
121:	RITDIITPSE RMRRLSR