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3.A.6.2.1
Flagellar protein export system.  Infrequent ATP hydrolysis by the FliI6FliJ ring is sufficient for gate activation, allowing processive translocation of export flagellar protein substrates for efficient flagellar assembly (Minamino et al. 2014). FliO has been identified as a flagellar basal body chaparone protein (Fabiani et al. 2017). The flagellar protein export apparatus switches its substrate specificity when hook length has reached approximately 55 nm, and the hydrophilic C-terminal domain of FlhB is involved in this switching process (Inoue et al. 2019).

Accession Number:P40727
Protein Name:FlhB aka STM1914
Length:383
Molecular Weight:42355.00
Species:Salmonella typhimurium [90371]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Flagellar proteins

Cross database links:

HEGENOM: HBG529770
RefSeq: NP_460871.1   
Entrez Gene ID: 1253435   
Pfam: PF01312   
BioCyc: STYP99287:STM1914-MONOMER   
KEGG: stm:STM1914   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0043064 P:flagellum organization
GO:0009306 P:protein secretion

References (3)

[1] “Molecular characterization of the Salmonella typhimurium flhB operon and its protein products.”  Minamino T.et.al.   8002587
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[3] “Purification and characterization of the CheZ protein of bacterial chemotaxis.”  Stock A.M.et.al.   3298217
Structure:
3B0Z     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAEESDDDKT EAPTPHRLEK AREEGQIPRS RELTSLLILL VGVCIIWFGG ESLARQLAGM 
61:	LSAGLHFDHR MVNDPNLILG QIILLIKAAM MALLPLIAGV VLVALISPVM LGGLIFSGKS 
121:	LQPKFSKLNP LPGIKRMFSA QTGAELLKAV LKSTLVGCVT GFYLWHHWPQ MMRLMAESPI 
181:	VAMGNALDLV GLCALLVVLG VIPMVGFDVF FQIFSHLKKL RMSRQDIRDE FKESEGDPHV 
241:	KGKIRQMQRA AAQRRMMEDV PKADVIVTNP THYSVALQYD ENKMSAPKVV AKGAGLIALR 
301:	IREIGAEHRV PTLEAPPLAR ALYRHAEIGQ QIPGQLYAAV AEVLAWVWQL KRWRLAGGQR 
361:	PPQPENLPVP EALDFMNEKN TDG