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3.A.1.3.14
Uptake system for L-cystine (Burguière et al., 2004)

Accession Number:P42199
Protein Name:TcyA (YckK)
Length:268
Molecular Weight:29514.00
Species:Bacillus subtilis [1423]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate Cystine

Cross database links:

HEGENOM: HBG698334
RefSeq: NP_388243.2   
Entrez Gene ID: 938298   
Pfam: PF00497   
KEGG: bsu:BSU03610   

Gene Ontology

GO:0030288 C:outer membrane-bounded periplasmic space
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006865 P:amino acid transport

References (5)

[1] “An operon encoding a novel ABC-type transport system in Bacillus subtilis.”  Rodriguez F.et.al.   7551042
[2] “The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes.”  Yamane K.et.al.   8969502
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[5] “Three different systems participate in L-cystine uptake in Bacillus subtilis.”  Burguiere P.et.al.   15262924

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKALLALFM VVSIAALAAC GAGNDNQSKD NAKDGDLWAS IKKKGVLTVG TEGTYEPFTY 
61:	HDKDTDKLTG YDVEVITEVA KRLGLKVDFK ETQWDSMFAG LNSKRFDVVA NQVGKTDRED 
121:	KYDFSDKYTT SRAVVVTKKD NNDIKSEADV KGKTSAQSLT SNYNKLATNA GAKVEGVEGM 
181:	AQALQMIQQG RVDMTYNDKL AVLNYLKTSG NKNVKIAFET GEPQSTYFTF RKGSGEVVDQ 
241:	VNKALKEMKE DGTLSKISKK WFGEDVSK