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3.A.1.3.14
Uptake system for L-cystine (Burguière et al., 2004)

Accession Number:P42200
Protein Name:TcyB (YckJ)
Length:234
Molecular Weight:26388.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cystine

Cross database links:

HEGENOM: HBG704821
RefSeq: NP_388242.1   
Entrez Gene ID: 938301   
Pfam: PF00528   
KEGG: bsu:BSU03600   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006865 P:amino acid transport

References (4)

[1] “An operon encoding a novel ABC-type transport system in Bacillus subtilis.”  Rodriguez F.et.al.   7551042
[2] “The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes.”  Yamane K.et.al.   8969502
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “Three different systems participate in L-cystine uptake in Bacillus subtilis.”  Burguiere P.et.al.   15262924

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFLNNLPALT LGTAIPWDLV QQSFWPILSG GIYYTIPLTI LSFIFGMILA LITALARMSK 
61:	VRPLRWVFSV YVSAIRGTPL LVQLFIIFYL FPAFNVTLDP FPSAVIAFSL NVGAYASEII 
121:	RASILSVPKG QWEAGYTIGM THQKTLFRVI LPQAFRVSIP PLSNTFISLI KDTSLASQIL 
181:	VAELFRKAQE IGARNLDQIL VIYIEAAFIY WIICFLLSLV QHVIERRLDR YVAK