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2.A.78.1.3
L-Methionine efflux pump (probably exports other neutral, hydrophobic amino acids as well; R. Figge, personal communication)

Accession Number:P43667
Protein Name:Hypothetical protein ygaH aka YgaH
Length:111
Molecular Weight:12024.00
Species:Escherichia coli [83333]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Methionine

Cross database links:

Genevestigator: P43667
EchoBASE: EB2775
EcoGene: EG12940
eggNOG: NOG14067
HEGENOM: HBG416921
RefSeq: AP_003255.1    NP_417168.1   
Entrez Gene ID: 945111   
Pfam: PF05437   
BioCyc: EcoCyc:G7406-MONOMER    ECOL168927:B2683-MONOMER   
KEGG: ecj:JW2658    eco:b2683   

Gene Ontology

GO:0015562 F:efflux transmembrane transporter activity
GO:0005304 F:L-valine transmembrane transporter activity
GO:0015829 P:valine transport

References (4)

[1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB.”  Lomovskaya O.et.al.   7730261

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSYEVLLLGL LVGVANYCFR YLPLRLRVGN ARPTKRGAVG ILLDTIGIAS ICALLVVSTA 
61:	PEVMHDTRRF VPTLVGFAVL GASFYKTRSI IIPTLLSALA YGLAWKVMAI I