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3.A.1.17.3
Putative hydroxymethylpyrimidine transport system, ThiXYZ (Rodionov et al., 2002). Regulated by TPP (thiamin) riboswitch. Potentially takes up a pyrimidine moiety of thiamin.

Accession Number:P44658
Protein Name:HI0357
Length:314
Molecular Weight:34961.00
Species:Haemophilus influenzae [727]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Hydroxymethylpyrimidine

Cross database links:

HEGENOM: HBG678689
RefSeq: NP_438519.1   
Entrez Gene ID: 949462   
BioCyc: HINF71421:HI_0357-MONOMER   
KEGG: hin:HI0357   

Gene Ontology

GO:0009228 P:thiamin biosynthetic process

References (2)

[1] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800
[2] “Two-dimensional map of the proteome of Haemophilus influenzae.”  Langen H.et.al.   10675023

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKTIIRYFSF VMGLMLTLPS FAKEKISIML DWYVNPDHAA IIVAQQKGFF EKNNLEVEII 
61:	EPADPALPPK LAAAEKVDLA VSYQPQLYQQ VAEGLPLVRV GSLISNPLNS VVVLKKSNLK 
121:	SLADLKGKKV GYSVSGFEDG LLDTMLHSIG LSNKDVELVN VNWSLSPSLL TGQVDAVIGA 
181:	FRNFELNQLA LEKQEGIAFF PEQYGVPAYD ELILVANKNS VTDKKTSAFL TALEQATSYL 
241:	QAHPNEAWQA FVSYKPNELN TPLNQLAWKD TLPFLANKPR QLDAKRYQQM AEFMQQKGLI 
301:	PKALALKEYA VEIE