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3.A.1.5.27
The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications (Vergauwen et al., 2010).

Accession Number:P45094
Protein Name:Dipeptide transport ATP-binding protein DppF
Length:327
Molecular Weight:36917.00
Species:Haemophilus influenzae [727]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate Glutathione

Cross database links:

HEGENOM: HBG758042
Entrez Gene ID: 950622   
Pfam: PF00005    PF08352   
KEGG: hin:HI1184   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0015197 F:peptide transporter activity
GO:0015031 P:protein transport

References (2)

[1] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800
[2] “Altered lipopolysaccharide characteristic of the I69 phenotype in Haemophilus influenzae results from mutations in a novel gene, isn.”  Preston A.et.al.   8550458

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTNEVKENTP LLNAIGLKKY YPVKKGLFAK PQQVKALDGV SFQLERGKTL AVVGESGCGK 
61:	STLGRLLTMI EEPTKGELYY KGHNFLENDS ETKALRRKKI QIVFQNPYAS LNPRKKIGSI 
121:	LEEPLIINTK LSAKERREKV LSMMEKVGLR AEFYDRYPHM FSGGQRQRIA IARGLMLDPD 
181:	VVVADEPVSA LDVSVRAQVL NLMMDLQDEL GLSYVFISHD LSVVEHIADE VMVMYLGRCI 
241:	EKGTTEQIFS NPQHPYTKAL LSATPRLSPN LRRERIKLTG ELPSPINPPK GCAFNPRCWK 
301:	ATEKCRENQP HLEQHTDGKL IACFHID