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3.A.1.5.27
The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications (Vergauwen et al., 2010).

Accession Number:P45096
Protein Name:Dipeptide transport system permease protein dppB
Length:333
Molecular Weight:36788.00
Species:Haemophilus influenzae [727]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Glutathione

Cross database links:

HEGENOM: HBG724229
Entrez Gene ID: 950100   
Pfam: PF00528   
KEGG: hin:HI1187   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015833 P:peptide transport
GO:0015031 P:protein transport

References (2)

[1] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800
[2] “Altered lipopolysaccharide characteristic of the I69 phenotype in Haemophilus influenzae results from mutations in a novel gene, isn.”  Preston A.et.al.   8550458

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFKFVFKRIL MVIPTFIAIT LITFALVHFI PGDPVEIMMG ERGLTAEVHQ QMMHQLGLDL 
61:	PLYQQYFHYI GNVIQGDFGA SFRTQQPVLT EFFTLFPATA ELAFFALFWS LLGGIILGTI 
121:	AAVKKDSWIS HTVTAASLTG YSMPIFWWGL ILILYVSPQL GLPQGGRLDN EFWIDTPTGF 
181:	MLIDSWLSGV SGAFENAVKS LILPAIVLGT VPLAIITRMT RSAMLEVLGE DYIRTAKAKG 
241:	LSYTRIVIVH ALRNALIPVV TVVGLIVAQL LSGAVLTETI FSWPGIGKWI IDAIQARDYP 
301:	VLQGSVLIIA TIIIVVNLTV DLLYGVVNPR IRH