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3.A.1.5.27
The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications (Vergauwen et al., 2010).

Accession Number:P51000
Protein Name:Dipeptide transport system permease protein dppC
Length:295
Molecular Weight:31840.00
Species:Haemophilus influenzae [727]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Glutathione

Cross database links:

HEGENOM: HBG729429
Entrez Gene ID: 950114   
Pfam: PF00528   
KEGG: hin:HI1186   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015833 P:peptide transport
GO:0015031 P:protein transport

References (2)

[1] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800
[2] “Altered lipopolysaccharide characteristic of the I69 phenotype in Haemophilus influenzae results from mutations in a novel gene, isn.”  Preston A.et.al.   8550458

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDTPLTFAP KTPLQEFWFY FKQNRGALIG LIFILIVALI SILAPYIAPF DPTEQNRTAL 
61:	LLPPAWYEGG NPAYLLGTDD IGRDILSRII YGTRISVFAG FIIVLLSCAF GTSLGLISGY 
121:	YGGVLDTIII RLIDIMLAIP NLLLTIVVVS ILEPSLANAT LAIAVVSIPS YVRLTRAAMM 
181:	NEKNRDYVTS SKVAGAGILR LMFIVILPNC LAPLIVQMTM GISNAILELA TLGFLGIGAK 
241:	PPTPELGTML SEARGFMQAA NWLVTIPGLV ILSLVLAFNL MGDGLRDALD PKLKQ