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3.A.6.2.1
Flagellar protein export system.  Infrequent ATP hydrolysis by the FliI6FliJ ring is sufficient for gate activation, allowing processive translocation of export flagellar protein substrates for efficient flagellar assembly (Minamino et al. 2014). FliO has been identified as a flagellar basal body chaparone protein (Fabiani et al. 2017). The flagellar protein export apparatus switches its substrate specificity when hook length has reached approximately 55 nm, and the hydrophilic C-terminal domain of FlhB is involved in this switching process (Inoue et al. 2019).

Accession Number:P54700
Protein Name:FliP aka FLAR aka STM1979
Length:245
Molecular Weight:26787.00
Species:Salmonella typhimurium [90371]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Flagellar proteins

Cross database links:

HEGENOM: HBG414116
RefSeq: NP_460932.1   
Entrez Gene ID: 1253500   
Pfam: PF00813   
BioCyc: STYP99287:STM1979-MONOMER   
KEGG: stm:STM1979   

Gene Ontology

GO:0009425 C:bacterial-type flagellum basal body
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0043064 P:flagellum organization
GO:0009306 P:protein secretion

References (2)

[1] “The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium: putative components for flagellar assembly.”  Ohnishi K.et.al.   9324257
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRRLLFLSLA GLWLFSPAAA AQLPGLISQP LAGGGQSWSL SVQTLVFITS LTFLPAILLM 
61:	MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI MSPVIDKIYV DAYQPFSEQK 
121:	ISMQEALDKG AQPLRAFMLR QTREADLALF ARLANSGPLQ GPEAVPMRIL LPAYVTSELK 
181:	TAFQIGFTIF IPFLIIDLVI ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLMGSLA 
241:	QSFYS