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3.A.6.2.1
Flagellar protein export system.  Infrequent ATP hydrolysis by the FliI6FliJ ring is sufficient for gate activation, allowing processive translocation of export flagellar protein substrates for efficient flagellar assembly (Minamino et al. 2014). FliO has been identified as a flagellar basal body chaparone protein (Fabiani et al. 2017). The flagellar protein export apparatus switches its substrate specificity when hook length has reached approximately 55 nm, and the hydrophilic C-terminal domain of FlhB is involved in this switching process (Inoue et al. 2019).

Accession Number:P54702
Protein Name:FliR aka FLAP aka STM1981
Length:264
Molecular Weight:28925.00
Species:Salmonella typhimurium [90371]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Flagellar proteins

Cross database links:

HEGENOM: HBG700695
RefSeq: NP_460934.1   
Entrez Gene ID: 1253502   
Pfam: PF01311   
BioCyc: STYP99287:STM1981-MONOMER   
KEGG: stm:STM1981   

Gene Ontology

GO:0009425 C:bacterial-type flagellum basal body
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006605 P:protein targeting

References (2)

[1] “The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium: putative components for flagellar assembly.”  Ohnishi K.et.al.   9324257
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIQVTSEQWL YWLHLYFWPL LRVLALISTA PILSERAIPK RVKLGLGIMI TLVIAPSLPA 
61:	NDTPLFSIAA LWLAMQQILI GIALGFTMQF AFAAVRTAGE FIGLQMGLSF ATFVDPGSHL 
121:	NMPVLARIMD MLAMLLFLTF NGHLWLISLL VDTFHTLPIG SNPVNSNAFM ALARAGGLIF 
181:	LNGLMLALPV ITLLLTLNLA LGLLNRMAPQ LSIFVIGFPL TLTVGIMLMA ALMPLIAPFC 
241:	EHLFSEIFNL LADIVSEMPI NNNP