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2.A.63.1.3
Multicomponent Na+:H+ antiporter, MnhABCDEFG

Accession Number:P60698
Protein Name:Na(+)/H(+) antiporter subunit G aka mnhG
Length:118
Molecular Weight:12819.00
Species:Staphylococcus aureus [1280]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

Pfam: PF03334   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005451 F:monovalent cation:hydrogen antiporter activity
GO:0015992 P:proton transport
GO:0006814 P:sodium ion transport

References (2)

[1] “A putative multisubunit Na+/H+ antiporter from Staphylococcus aureus.”  Hiramatsu T.et.al.   9852009
[2] “Catalytic properties of Staphylococcus aureus and Bacillus members of the secondary cation/proton antiporter-3 (Mrp) family are revealed by an optimized assay in an Escherichia coli host.”  Swartz T.H.et.al.   17293423

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIKIILISLA LIFVIIGALI SALAAIGLLR LEDVYSRAHA AGKASTLGAM SLLFGTFLYF 
61:	IATQGFVNMQ LIVAIIFVLI TGPLSSHMIM KAAYNIKTPY TKKTKVDEIS EDLKDTKL