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9.A.48.1.1
The Unconventional Protein Secretion System, UPSS (Giuliani et al., 2011).  Secretes FGF1 and Epimorphin (syntaxin 2) (Hirai et al. 2007)

Accession Number:P61148
Protein Name:Fgf1 aka Heparin-binding growth factor 1 precursor
Length:155
Molecular Weight:17418.00
Species:Mus musculus (Mouse) [10090]
Location1 / Topology2 / Orientation3: Secreted1
Substrate proteins

Cross database links:

Genevestigator: P61148
eggNOG: roNOG09394
HEGENOM: HBG715603
RefSeq: NP_034327.1   
Entrez Gene ID: 14164   
Pfam: PF00167   
KEGG: mmu:14164   

Gene Ontology

GO:0005829 C:cytosol
GO:0005615 C:extracellular space
GO:0005578 C:proteinaceous extracellular matrix
GO:0008083 F:growth factor activity
GO:0008201 F:heparin binding
GO:0001525 P:angiogenesis
GO:0034605 P:cellular response to heat
GO:0001759 P:induction of an organ
GO:0030324 P:lung development
GO:0051781 P:positive regulation of cell division
GO:0050679 P:positive regulation of epithelial cell prol...
GO:0010552 P:positive regulation of gene-specific transc...
GO:0001934 P:positive regulation of protein amino acid p...

References (4)

[1] “Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis.”  Hebert J.M.et.al.   2318343
[2] “Cloning and characterization of the mouse Fgf-1 gene.”  Madiai F.et.al.   8972905
[3] “Characterization of the 1B promoter of fibroblast growth factor 1 and its expression in the adult and developing mouse brain.”  Alam K.Y.et.al.   8939980
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAEGEITTFA ALTERFNLPL GNYKKPKLLY CSNGGHFLRI LPDGTVDGTR DRSDQHIQLQ 
61:	LSAESAGEVY IKGTETGQYL AMDTEGLLYG SQTPNEECLF LERLEENHYN TYTSKKHAEK 
121:	NWFVGLKKNG SCKRGPRTHY GQKAILFLPL PVSSD