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3.A.1.26.4
ThiW/CbiQ homologues (ThiW: 697 aas; M-C-C) (No known binding receptor) (Rodionov et al., 2009)

Accession Number:P63399
Protein Name:ThiW
Length:697
Molecular Weight:72835.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_216842.1    NP_336866.1   
Entrez Gene ID: 888184    924025   
Pfam: PF00005   
KEGG: mtc:MT2388    mtu:Rv2326c   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0006810 P:transport

References (2)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MCCAVCGPEP GRIGEVTPLG PCPAQHRGGP LRPSELAQAS VMAALCAVTA IISVVVPFAA 
61:	GLALLGTVPT GLLAYRYRLR VLAAATVAAG MIAFLIAGLG GFMGVVHSAY IGGLTGIVKR 
121:	RGRGTPTVVV SSLIGGFVFG AAMVGMLAAM VRLRHLIFKV MTANVDGIAA TLARMHMQGA 
181:	AADVKRYFAE GLQYWPWVLL GYFNIGIMIV SLIGWWALSR LLERMRGIPD VHKLDPPPGD 
241:	DVDALIGPVP VRLDKVRFRY PRAGQDALRE VSLDVRAGEH LAIIGANGSG KTTLMLILAG 
301:	RAPTSGTVDR PGTVGLGKLG GTAVVLQHPE SQVLGTRVAD DVVWGLPLGT TADVGRLLSE 
361:	VGLEALAERD TGSLSGGELQ RLALAAALAR EPAMLIADEV TTMVDQQGRD ALLAVLSGLT 
421:	QRHRTALVHI THYDNEADSA DRTLSLSDSP DNTDMVHTAA MPAPVIGVDQ PQHAPALELV 
481:	GVGHEYASGT PWAKTALRDI NFVVEQGDGV LIHGGNGSGK STLAWIMAGL TIPTTGACLL 
541:	DGRPTHEQVG AVALSFQAAR LQLMRSRVDL EVASAAGFSA SEQDRVAAAL TVVGLDPALG 
601:	ARRIDQLSGG QMRRVVLAGL LARAPRALIL DEPLAGLDAA SQRGLLRLLE DLRRARGLTV 
661:	VVVSHDFAGM EELCPRTLHL RDGVLESAAA SEAGGMS