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3.A.1.26.4
ThiW/CbiQ homologues (ThiW: 697 aas; M-C-C) (No known binding receptor) (Rodionov et al., 2009)

Accession Number:P64997
Protein Name:Uncharacterized protein Rv2325c/MT2387
Length:282
Molecular Weight:29956.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

HEGENOM: HBG564782
RefSeq: NP_216841.1    NP_336865.1   
Entrez Gene ID: 886271    924024   
Pfam: PF02361   
KEGG: mtc:MT2387    mtu:Rv2325c   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015087 F:cobalt ion transmembrane transporter activity
GO:0009236 P:cobalamin biosynthetic process
GO:0006824 P:cobalt ion transport

References (2)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MTTTSAPARN GTRRPSRPIV LLIPVPGSSV IHDLWAGTKL LVVFGISVLL TFYPGWVTIG 
61:	MMAALVLAAA RIAHIPRGAL PSVPRWLWIV LAIGFLTAAL AGGTPVVAVG GVQLGLGGAL 
121:	HFLRITALSV VLLALGAMVS WTTNVAEISP AVATLGRPFR VLRIPVDEWA VALALALRAF 
181:	PMLIDEFQVL YAARRLRPKR MPPSRKARRQ RHARELIDLL AAAITVTLRR ADEMGDAITA 
241:	RGGTGQLSAH PGRPKLADWV TLAITAMASG TAVAIESLIL HS