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4.A.2.1.11
The FryABC putative transporter of unknown function.  FryA is a 3-domain multiphosphoryl transfer protein: EI-HPr-IIAFru (Reizer et al., 1995).

Accession Number:P69808
Protein Name:Fructose-like phosphotransferase enzyme IIB component 1
Length:108
Molecular Weight:11735.00
Species:Escherichia coli (strain K12) [83333]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate Unknown

Cross database links:

Genevestigator: P69808
EchoBASE: EB3907
EcoGene: EG14155
eggNOG: COG1445
HEGENOM: HBG564028
RefSeq: AP_002987.1    NP_416888.1   
Entrez Gene ID: 949087   
Pfam: PF02302   
BioCyc: EcoCyc:G7250-MONOMER    ECOL168927:B2387-MONOMER   
KEGG: ecj:JW5389    eco:b2387   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0016020 C:membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (3)

[1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
Structure:
2KYR     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKKLIALCA CPMGLAHTFM AAQALEEAAV EAGYEVKIET QGADGIQNRL TAQDIAEATI 
61:	IIHSVAVTPE DNERFESRDV YEITLQDAIK NAAGIIKEIE EMIASEQQ