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3.A.1.5.11
Glutathione porter, YliABCD or GsiABCD (Suzuki et al., 2005)

Accession Number:P75797
Protein Name:Putative binding protein yliB [Precursor]
Length:512
Molecular Weight:56470.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate Glutathione

Cross database links:

Genevestigator: P75797
EchoBASE: EB3246
EcoGene: EG13473
eggNOG: COG0747
HEGENOM: HBG688042
DIP: DIP-12697N
RefSeq: AP_001461.1    NP_415351.1   
Entrez Gene ID: 945459   
Pfam: PF00496   
BioCyc: EcoCyc:YLIB-MONOMER    ECOL168927:B0830-MONOMER   
KEGG: ecj:JW5111    eco:b0830   

Gene Ontology

GO:0042597 C:periplasmic space
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (6)

[1] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography.”  Fountoulakis M.et.al.   10493123
[5] “The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.”  Suzuki H.et.al.   16109926
[6] “Structural genomics of highly conserved microbial genes of unknown function in search of new antibacterial targets.”  Abergel C.et.al.   14649299
Structure:
1UQW     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MARAVHRSGL VALGIATALM ASCAFAAKDV VVAVGSNFTT LDPYDANDTL SQAVAKSFYQ 
61:	GLFGLDKEMK LKNVLAESYT VSDDGITYTV KLREGIKFQD GTDFNAAAVK ANLDRASDPA 
121:	NHLKRYNLYK NIAKTEAIDP TTVKITLKQP FSAFINILAH PATAMISPAA LEKYGKEIGF 
181:	YPVGTGPYEL DTWNQTDFVK VKKFAGYWQP GLPKLDSITW RPVADNNTRA AMLQTGEAQF 
241:	AFPIPYEQAT LLEKNKNIEL MASPSIMQRY ISMNVTQKPF DNPKVREALN YAINRPALVK 
301:	VAFAGYATPA TGVVPPSIAY AQSYKPWPYD PVKARELLKE AGYPNGFSTT LWSSHNHSTA 
361:	QKVLQFTQQQ LAQVGIKAQV TAMDAGQRAA EVEGKGQKES GVRMFYTGWS ASTGEADWAL 
421:	SPLFASQNWP PTLFNTAFYS NKQVDDFLAQ ALKTNDPAEK TRLYKAAQDI IWQESPWIPL 
481:	VVEKLVSAHS KNLTGFWIMP DTGFSFEDAD LQ