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3.A.1.5.11
Glutathione porter, YliABCD or GsiABCD (Suzuki et al., 2005)

Accession Number:P75798
Protein Name:Inner membrane ABC transporter permease protein yliC
Length:306
Molecular Weight:34066.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Glutathione

Cross database links:

Genevestigator: P75798
EchoBASE: EB3247
EcoGene: EG13474
eggNOG: COG0601
HEGENOM: HBG724229
RefSeq: AP_001462.1    NP_415352.1   
Entrez Gene ID: 945460   
Pfam: PF00528   
BioCyc: EcoCyc:YLIC-MONOMER    ECOL168927:B0831-MONOMER   
KEGG: ecj:JW0815    eco:b0831   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (5)

[1] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.”  Suzuki H.et.al.   16109926
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLNYVIKRLL GLIPTLFIVS VLVFLFVHML PGDPARLIAG PEADAQVIEL VRQQLGLDQP 
61:	LYHQFWHYIS NAVQGDFGLS MVSRRPVADE IASRFMPTLW LTITSMVWAV IFGMAAGIIA 
121:	AVWRNRWPDR LSMTIAVSGI SFPAFALGML LIQVFSVELG WLPTVGADSW QHYILPSLTL 
181:	GAAVAAVMAR FTRASFVDVL SEDYMRTARA KGVSETWVVL KHGLRNAMIP VVTMMGLQFG 
241:	FLLGGSIVVE KVFNWPGLGR LLVDSVEMRD YPVIQAEILL FSLEFILINL VVDVLYAAIN 
301:	PAIRYK