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4.A.2.1.9
The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence (Patron et al. 2015).

Accession Number:Q1R4S9
Protein Name:Putative phosphotransferase system (PTS), fructose-specific
Length:156
Molecular Weight:17425.00
Species:Escherichia coli (strain UTI89 / UPEC) [364106]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Tagatose, psicose, Sorbose

Cross database links:

eggNOG: COG1762
HEGENOM: HBG697201
RefSeq: YP_543166.1   
Entrez Gene ID: 3991484   
Pfam: PF00359   
BioCyc: ECOL364106:UTI89_C4207-MONOMER   
KEGG: eci:UTI89_C4207   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach.”  Chen S.L.et.al.   16585510

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDITKILNTN RVILDMQATN KAEAIEELTN LLKKDGAIDC RETFIKDVWQ REAEGSTGFE 
61:	NHIAIPHGKS SAVINTTLAI GRTRQDIPWE TLDGSSVRCI ILFAVRLEDQ NTTHIRLLSQ 
121:	VAGALADDDI IEQLLVETSP QKIIDLFSQY AQSDVF