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2.A.6.2.26
The multidrug efflux pump, VmeAB-VpoC (Matsuo et al., 2007).  There are 11 RND-type efflux transporters in Vibrio parahaemolyticus, and several (VmeCD, VmeEF and VmeYZ) contribute not only to intrinsic drug resistance but also to virulence (Matsuo et al. 2013).

Accession Number:Q2AAU4
Protein Name:VmeA
Length:379
Molecular Weight:40404.00
Species:Vibrio parahaemolyticus [670]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate drugs

Cross database links:

Pfam: PF00529   

Gene Ontology

GO:0016020 C:membrane
GO:0008565 F:protein transporter activity
GO:0009306 P:protein secretion

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MRRRTTLSLL IASSLFMAGC QPSQEGTEQG GGAAPATEVN VLTVEPVRQA LTVELPGRSR 
61:	AFKEAEVRPQ VTGIISERNF VEGGVVEKGQ SLYQIDDSSF QADLLSAEAE LIRAQASEES 
121:	TFATVKRYRA LITKKSISQQ DLDEAEAAYK EAKAQVLVAK AKINTAKINL TYTRVKAPIS 
181:	GVISKSNVTA GALVTANQAD KLTTIQQLDP INVDIVQSSA QLLRLKAALS QGHMQEDQSA 
241:	QVALTLEDGS TYEHKGTMKF TEVNVDESTG SVTLRAEFPN PDGLLLPGMF VRATVITGVD 
301:	PSAILIPQNT VTRDATGKAS VMTVSADNTV AITPVITAEV IDNQWRIIDG LKAGDQVITA 
361:	GLQKVRPGSP VTIQTGEQG