TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.124.1
The 3-component nisin immunity exporter, NisFEG. Contains an essential E-loop (Okuda et al., 2010).

Accession Number:Q48597
Protein Name:NisF
Length:225
Molecular Weight:24682.00
Species:Lactococcus lactis [1358]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Nisin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3.”  Siegers K.et.al.   7793910

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQVKIQNLSK TYKEKQVLQD ISFDIKSGTV CGLLGVNGAG KSTLMKILFG LISADTGKIF 
61:	FDGQEKTNNQ LGALIEAPAI YMNLSAFDNL KTKALLFGIS DKRIHETLEV IGLAETGKKR 
121:	AGKFSLGMKQ RLGIGMAILT EPQFLILDEP TNGLDPDGIA ELLNLILKLK AKGVTILISS 
181:	HQLHEISKVA SQIIILNKGK IRYNRANNKE DDIEQLFFKI VHGGM