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3.A.1.17.3
Putative hydroxymethylpyrimidine transport system, ThiXYZ (Rodionov et al., 2002). Regulated by TPP (thiamin) riboswitch. Potentially takes up a pyrimidine moiety of thiamin.

Accession Number:Q57306
Protein Name:HI0355
Length:245
Molecular Weight:27098.00
Species:Haemophilus influenzae [727]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Hydroxymethylpyrimidine

Cross database links:

HEGENOM: HBG754934
RefSeq: NP_438518.1   
Entrez Gene ID: 949458   
Pfam: PF00528   
BioCyc: HINF71421:HI_0355-MONOMER   
KEGG: hin:HI0355   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKIRLLKPLL IVGVLLMIWQ MVATLGSFPH YIFPSPQAVR QQLFTHAELL WQHTQVTLLE 
61:	ICLGLLLGFL FGLISALLLS FSRQISAVLL PILVISQAIP VFAIAPLLVL WFGYGMASKI 
121:	VMSVLIIYFP VTAACYDGLR NTPQAWLDLA KTFNISPLRL LLKVRLPAAL PAFASGLRIA 
181:	VSVAPIGAVV GEWVGSSEGL GYLMIHANAR MQVDLMFAAL LILVSISLCL YFSIDWLLHR 
241:	FIWSV