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3.A.1.122.14
ABC transporter of unknown function, but aspects of its structure and mechanism of action are known (Yuan et al. 2001; Zoghbi and Altenberg 2013).  Nucleotide-binding domain dimerization occurs as a result of binding to the natural nucleotide triphosphates, ATP, GTP, CTP and UTP, as well as the analog ATP-gamma-S. All the natural nucleotide triphosphates are hydrolyzed at similar rates, whereas ATP-gamma-S is not hydrolyzed. The non-hydrolyzable ATP analog AMP-PNP, frequently assumed to produce the nucleotide-bound conformation, failed to elicit nucleotide-binding domain dimerization (Fendley et al. 2016).

Accession Number:Q58207
Protein Name:Uncharacterized ABC transporter permease MJ0797
Length:367
Molecular Weight:41039.00
Species:Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [243232]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYFELAKRNL KRNLLRSILA LLGIIIGVAA ISSLGILGGG LKQGIMENLG SISNYIIVFP 
61:	NYQNGYTSFD KRDIEKLRVL NCKVIPVYAT SDFVYIKGKN RKAYANIFGI DKNDIKYLNL 
121:	KVKVSDTSVA VDTFFSNVND VNVGNQLEIK NISLRICGIY NSTFLFPDNS LILTAKTYRR 
181:	FYGENNYNYS RIILYVKNIN DIDKIKNETD KILNRKEKKC IIISLNSILE AINGVITKVS 
241:	YFLMGIGAIS LLVAGIGIGN VMLMSVVERT TEIGVMRSIG ASKKDIIILF LYEALILGVI 
301:	GSLIGAFLSL FFGYLIVHYL LKTSLSYYAI FYMIIGIIFG ILTSLISALY PAYKASKLDP 
361:	IKSLRNE