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3.A.1.205.13
The putative sterol uptake transporter, Aus1 (also protects against antifungal azoles such as fluconazole and itraconazole; (Nakayama et al., 2007).

Accession Number:Q6FUR1
Protein Name:ABC transporter
Length:1398
Molecular Weight:157977.00
Species:Candida glabrata (Yeast) [5478]
Number of TMSs:13
Substrate sterols, Azoles, Fluconazole, Itraconazole

Cross database links:

eggNOG: fuNOG14278 fuNOG14278 fuNOG14278
HEGENOM: HBG323792 HBG323792 HBG323792
Entrez Gene ID: 2887947   
Pfam: PF01061    PF00005    PF06422   
KEGG: cgr:CAGL0F01419   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...

References (2)

[1] “Genome evolution in yeasts.”  Dujon B.et.al.   15229592
[2] “The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum.”  Nakayama H.et.al.   17913716

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSLADYFTPV PNASVTFEGT TVNLNETATG SAHSHAEDPE FGEKLPLPSV SPCENGQVVD 
61:	LTFQATAGEM VLVLGAPTSG IFKSLFHAHK HLSYSPQGSI RFKDNEFKAY SSKSPHQIIY 
121:	NNEQDVHFPF LTVNQTVDFA LSCKFDIPKE ERENMRNELL REFGLSHVGD TIVGNDYFRG 
181:	VSGGERKRIS IIETFIANGS VYLWDNSTKG LDSSTALDFL TILQKMARTT RSVNLVRISQ 
241:	ASDKIVEKFD KILMLSDSYQ VFYGTVDECL HHFRDNLGIK KDPNDCIIEY LTSILNFQFR 
301:	TKSLDITGSS EDLDLKDTDH NEQTFSGIAS SLCSEVDLYT QWKKSSYYQD IKEQIGAFNV 
361:	ENKADGNHIN PEDVTKTFDI PLKKQILYCT KRAFQRSLGD KAYMISQVIS VIIQSLVIGS 
421:	LFYDIPMTTI GSFSRGSLTF FSILFFTFLS LADMPIAFQR QAVVKKQTLL HFYFNSVETL 
481:	ATTLFDYCFK FCLVVIFTII LYFLAHLQYN AARFFIFLLF LSVYNFCMVS LFSLTTMFTP 
541:	TISLANLFAG ILLLAIAMYA SYVIYMKDMH PWFVWIAYLN PAMYAMESIL ANEMFNLKLD 
601:	CTESVVPRGP TYQNVPVTNK ACAWQGATLG NDYVRGKDYL KNGLSYKYSH VWRNFGILIG 
661:	FLCFFIAMNL FASEYIKPLF YNDGPEAVQH FINRWFRRSA THSTTSSSSP ENIKLKEDVV 
721:	VKSASLSSTS SLSSSETAKS NPFADKTVQA QKHVISWKNI NYTVGGDKRL INNVSGYIGS 
781:	GLTALMGESG AGKTTLLNVL SQRTESGVVS GEILIDGKPL TNENAFRRSI GFVQQQDIHL 
841:	ELLTVKESLE ISSELRGDGD MEYVESISEL LKLPLDSLVR ELNPTQRKLL SIGVELVTKP 
901:	SLLLFLDEPT SGLDAEAALT IVQFLKKLSL QGQAIFCTIH QPSKSVISYF DNIYLLKRGG 
961:	ECVYFGPTSE ACGYFMSYDK SLTYDPESDN PADFVIDVVG NNESMEEMDD KADFAIREEN 
1021:	PWSTRWENSH ERKNIDETVV RLEQEAAASG VDFTTAVWEQ PSYMKQLIMI TKRQYTCTRR 
1081:	DRSYIAAKYL LNGGAGLFIG FSFWKIKHTI SGLQDTIFFC FMALCVSSPL INQVQDKALQ 
1141:	SKEVFIARES RSNTYHWTCL LLAQFIIELP LAMSSSTLFF VCAFFCCGFD NSGKVAGVFY 
1201:	LNYILFSAYY LTLGLWLIYT APNLQTAAVF VAFIYSFTAS FCGVMQPYAL FPGFWKFMYR 
1261:	VSPYTYFVDT FVSTLLHNRK VICNTGEMVP GQPTGGKTCG QFFKAYIDEY GGWLKNPNTF 
1321:	TVCAYCTYDT GDDFLKQQNM SHSHIWRNYG IEWAFVAFNF FAMFAGYYLT YVAKVWPKVF 
1381:	KFIMKLIPTG IKSRASKD