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1.A.9.1.12
Nicotinic acetylcholine receptor with three subunits, non-alpha subunit ShAR2beta of 545 aas, as well as two additional "non-alpha subunits of 714 and 736 aas, respectively, all with 6 TMSs, 1 N-terminal, 4 central, and 1 C-terminal (Bentley et al. 2007). 

Accession Number:Q6TMY2
Protein Name:Nicotinic acetylcholine receptor non-alpha subunit
Length:736
Molecular Weight:84341.00
Species:Schistosoma haematobium (Blood fluke) [6185]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate inorganic cations

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTLCHILCY IVLYQILCIT WIGKVDSGHS EKRLLKYLFD QKRWDAHNPM ERPVSVDGKP 
61:	VQVFLKCFLN QIMDVDEKNQ VLSTIIWLDL KWSDYHFHWN ASDYENIRQI NLPPERIWKP 
121:	DILLYNSASE KFDQIFPTKV IVRNTGNIQW VPPGLFHSIC DIEVNWFPFD SQNCIMKLGT 
181:	WTYQGNTVDL KLQCDNETED VDQPCHYMND VDLSTYLAHS EWALESASIK RNIQTYGGED 
241:	QTYIDVTIYV YMQRRALYYM FNIIIPCMIM SMMALLVFTL PPEANEKIVL GVTTLLSLTM 
301:	LLQLVADKLP QTSSGNPVLV LYFTCTMILC SLSLVCAVVL LNCHHHTGGI VYVPWWIETL 
361:	INIWLASILR IDHDLSDPNN NDNNNHHGDN NNNKTEPNLK NSKEKLIPSE NSFQLDQYDY 
421:	DKINHHIHLN HSYNNNSGNG NNNARNATVW SNIIDMNSEF RPAIVIHKPF KHDNNHNSNM 
481:	KKSLFMNQFK LKSELQSRIQ QNYFIDLDPD YDRDRGDQHQ LSTDLSGKPL NNMPYHTITT 
541:	TTIPEDRGNS RTNATSRLQY TCKRNLTEKS KYFNKTIPRF HLSSSSSSSS SNESPQDSSL 
601:	SSSPTPLPPA SSSSSSSSSS SSSRSTVFSS PNRITDPSSS SPFKQNHNNN DSMNFDIILL 
661:	KLKQISNELR FITSDMHNKD KEIKTSNQWR LACRVLDRLC LLIFTALNLF TTLGILTSAP 
721:	TVIKAFTSRG APSQPM