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1.A.9.1.12
Nicotinic acetylcholine receptor with three subunits, non-alpha subunit ShAR2beta of 545 aas, as well as two additional "non-alpha subunits of 714 and 736 aas, respectively, all with 6 TMSs, 1 N-terminal, 4 central, and 1 C-terminal (Bentley et al. 2007). 

Accession Number:Q6TMY3
Protein Name:Nicotinic acetylcholine receptor alpha subunit
Length:714
Molecular Weight:81316.00
Species:Schistosoma haematobium (Blood fluke) [6185]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate inorganic cations

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLIMNSIIKL CFGLFMFIDV VLSGLYEKRL LKYLFDSSRP DAHNPIERPS ANDTETLNVS 
61:	VKFFLNQVMD VDEKNQVLTT IIWMDLIWND YHFLWNPKEF GNITTLNLPY TAVWRPDILL 
121:	YNCADEKFDR TFPTNTIIKH DGTVQWMPPG LFKSTCNIDI LWFPFDEQSC ILKFGSWTYY 
181:	GDQINFQLQC INASQPDCTQ VGTVDLSEYS RNGEFHLSGS SVRRYAQRYE CCDYDFVDVK 
241:	IAITLQRRAL YYVFNLIVPC LLISGMALMV FMLPPDAGEK ISLGVTILLS LTMFLQLVAD 
301:	KLPQTSEAIP LIGIYFSCTM FMCSLSIVFT VLVLNYHHRS ADCIAVPAWI RNIVNTYLAK 
361:	LMCMEPPKRS QIIEVEDISS SISDNFMENY PNTKKSQNET LIKGGARGEQ QQQQEGGGGE 
421:	EEDDEEGHIG AKTFVGWNYD TTNMMNSNIN PVYMKKHLFT NSPICINGNL KTTTLPMINQ 
481:	SMNNIDYQLH NTVNERTPKN AIANVIDLDD DFRATARFGN TTTTTTNTTH TTTTTHTNNS 
541:	NIFINMHEKQ TILNNNTKLK MNTDLLSSVT VTNQSLTVQS PYRLYNSVGN FNSKSVPLTP 
601:	ISTLEHVQNV FPDEFSDLSK NGVSFDRQIE PDPLSISIDL LNLYKPDLEI IINELHFITK 
661:	KLRDNEKESL ISLEWKFAAR VIDRFCLVIF SVCNIVVTFA ILCSAPNLIA SFMP