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3.A.1.14.17
Heme acquisition ABC uptake transporter, IsdDEF (Liu et al., 2008)

Accession Number:Q7A651
Protein Name:IsdF
Length:322
Molecular Weight:35175.00
Species:Staphylococcus aureus (strain N315) [158879]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heme

Cross database links:

eggNOG: COG0609
HEGENOM: HBG700016
RefSeq: NP_374251.1   
Entrez Gene ID: 1123808   
Pfam: PF01032   
BioCyc: SAUR158879:SA0981-MONOMER   
KEGG: sau:SA0981   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Whole genome sequencing of meticillin-resistant Staphylococcus aureus.”  Kuroda M.et.al.   11418146

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MMIKNKKKLL FLCLLVILIA TAYISFVTGT IKLSFNDLFT KFTTGSNEAV DSIIDLRLPR 
61:	ILIALMVGAM LAVSGALLQA ALQNPLAEAN IIGVSSGALI MRALCMLFIP QLYFYLPLLS 
121:	FIGGLIPFLI IILLHSKFRF NAVSMILVGV ALFVLLNGVL EILTQNPLMK IPQGLTMKIW 
181:	SDVYILAVSA LLGLILTLLL SPKLNLLNLD DIQARSIGFN IDRYRWLTGL LAVFLASATV 
241:	AIVGQLAFLG IIVPHVVRKL VGGNYRVLIP FSTVIGAWLL LVADLLGRVI QPPLEIPANA 
301:	ILMIVGGPML IYLICQSQRN RI