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2.A.63.1.2
Multicomponent Na+:H+ antiporter, NhaA-G. Nha1,2,3,(4)

Accession Number:Q7AJV8
Protein Name:NhaA
Length:804
Molecular Weight:89095.00
Species:Bacillus halodurans [86665]
Number of TMSs:19
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

HEGENOM: HBG672487
Entrez Gene ID: 894323   
Pfam: PF00361    PF00662   
KEGG: bha:BH1319   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015077 F:monovalent inorganic cation transmembrane transporter activity
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0042773 P:ATP synthesis coupled electron transport
GO:0030004 P:cellular monovalent inorganic cation homeostasis

References (1)

[1] “Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.”  Takami H.et.al.   11058132

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLLHWATVS PFLLAIFIPI LYKYTRSIHT GWFVLVLPLV LFGYFLSLLP ITSNGGVIHE 
61:	TIPWVPSLGI NFTVYVDGLS LLFALLITGI GTLVALYSIY YLSKKTEKLN NFYVYLLMFM 
121:	GAMLGVVLSD NLIVLYVFWE LTSLASSLLI SYWFHREKST YGAQKSMLIT VFGGFAMLGG 
181:	FSLLYVITGT FSIREIIEQA DAVLASTLFL PAMLLVLLGA FTKSAQFPFH IWLPDAMEAP 
241:	TPVSAYLHSA TMVKAGLYLV ARLTPVFGGT PEWFWLLAGF GIITLCWGSI SAVRQKDLKS 
301:	ILAFSTISQL GLIMCLFGLG SATLHFDPTD SMIKFYATAT LAAVFHLINH ATFKGSLFMT 
361:	VGIIDHETGT RDIRKLGGLM AIMPVTFTVS LIGLAAMAGL PPFNGFLSKE MFFSGVVTAT 
421:	TLGIFNMETW GFLFPVLAWV ASVFTFVYCA IMFFRTFTGE FKKENYDVHV HEAPMGMLIS 
481:	PVILGSLVVI FGLFPNLLTY TIIEPAVTAI LGADVFGGGE ANIYLWHGFN PELFMTIAVV 
541:	AFGTLIFMNM KKWQQTAFYL RERDPLNRVY DSSLDWLIKG SQGITRVQMT GMLRDYFAYM 
601:	CVFMILLFGY TMVRYNAFAI DTVNVSVISP YMWVLTLVFI GSTLAIPFIN HRITAIIVVG 
661:	VIGFLLALFF VIFRAPDLAL TQLLVETVTV VLFMLAFYHL PELRKEKFTP RFNLVNLFIS 
721:	IGVGGLVTLI ALSSFALGTE AGLGTISEYF IENSKELAGG YNMVNVILVD FRGLDTLLEV 
781:	LVLGIAALGV IAMIKLRMTG REDV