TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.5.24
The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) (Novikova et al., 2007).

Accession Number:Q7CQ74
Protein Name:YejB
Length:364
Molecular Weight:40304.00
Species:Salmonella typhimurium [90371]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

HEGENOM: HBG724229
RefSeq: NP_461161.1   
Entrez Gene ID: 1253739   
Pfam: PF00528   
BioCyc: STYP99287:STM2217-MONOMER   
KEGG: stm:STM2217   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGAYLIRRLL LVIPTLWAII TINFFIVQIA PGGPVDQAIA AIEFGQGGAL PGASGEGVRA 
61:	SHAQTGVGNI SDSHYRGGRG LDPEVIAEIT HRYGFDKPLH ERYFKMLRDY LSFDFGDSLF 
121:	RSASVLTLIK DSLPVSITLG LWSTLIIYLV SIPLGIRKAV HNGSRFDVWS SAFIIIGYAI 
181:	PAFLFAILLI VFFAGGSYYD IFPLRGLVSA NFDTLPWYQK ITDYLWHITL PVLATVIGGF 
241:	AALTMLTKNS FLDEVRKQYV VTARAKGVSE KNILWKHVFR NAMLLVIAGF PATFISMFFT 
301:	GSLLIEVMFS LNGLGLLGYE ATVSRDYPVM FGTLYIFTLI GLLLNILSDI SYTLVDPRID 
361:	FEGR