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3.A.1.1.20
The fructooligosaccharide porter, MsmEFGK (Barrangou et al., 2003)

Accession Number:Q7WWR0
Protein Name:Substrate-binding protein MsmE
Length:431
Molecular Weight:48128.00
Species:Lactobacillus acidophilus [1579]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Fructooligosaccharides

Cross database links:

HEGENOM: HBG428314
RefSeq: YP_193416.1   
Entrez Gene ID: 3252767   
Pfam: PF01547   
BioCyc: LACI272621:LBA0502-MONOMER   
KEGG: lac:LBA0502   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (2)

[1] “Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus.”  Barrangou R.et.al.   12847288
[2] “Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.”  Altermann E.et.al.   15671160

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKKWKLGVAA IATVAALSLT GCSNNSQSGS SNNKNVTMWV HFSNTDPEGK ALQKNINDFN 
61:	KENKHGYKAK VQYIPRSGSG GGYEDKINAA LNSGSLPDVL TLDAPNTAAY AHSKIIQPID 
121:	KYITNKDDIL PTIIKQGTYK GKLYAAGYSE SSIGFYYNKK MFKEAGIKDS EIATLQHPWT 
181:	WTQFKDICKR LKNHFHEPAI NMNLNDHSEM ALYSLAPFVW SAGGSITNPA GTKAVGYFNS 
241:	KQTTSAFQLI QDMVKDGYTT ISPKDKGFET GKYAMMMTGT WEVQTLQNQY KNLQWGVMPY 
301:	PVSPATHKEV SPTGSWQYAM SSAAKNKKAA GALINFLMSK KCMYRSDMAN TVLPARKSVS 
361:	KMMMPKVNEQ MRFFIKQNQT TGHARPVLVN YPQVTRTFAD TVQNVTLYKK NPNVQKVMNE 
421:	QAKVIQKYLE K