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3.A.1.135.9
Multidrug exporter, EfrEF.  Mediates efflux of fluorescent substrates and confers resistance towards multiple dyes and drugs including fluoroquinolones (Hürlimann et al. 2016).

Accession Number:Q832J9
Protein Name:ABC transporter, ATP-binding/permease protein
Length:592
Molecular Weight:65881.00
Species:Enterococcus faecalis (strain ATCC 700802 / V583) [226185]
Number of TMSs:5
Substrate drugs, Fluoroquinolones

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKTMNLQSF KRFWKMIKPE HPIFYGLMIC SLIGNLLIVA MTYIMAIGID NLLEAIKRVG 
61:	LKGMTLPLVE EALLGPVLLL ILFSIISSIT SFIQERAMAS LSERVTLRIR KEVTKKFKTL 
121:	PMAFFDNHQV GDIISRSTTG LNQLSQVLLT GINQFFTSVV TILFAGIMLF YIDAKLTILV 
181:	LLLIGGSTFM TTKIANKNKV FADQSQAELG QLNNKMEEYL AGNLVTKTFN QQQNAEKTID 
241:	AVNQQHYRAF KKAQFLNFAI YPAIRFINQL AFIISAILGA MLVLSGGITI GFLQAYLQYI 
301:	NQISEPISTA SYVINSIQAA MASIDRIFVI LDEADEQPEA THLETISSPK GAIEFKNVQF 
361:	GYTPEKILMK NVDFSVQPKK TVAIVGPTGA GKTTLVNLLM RFYEINQGAI TFDGIDITKL 
421:	SRQNLRNLFG MVLQNTWLFE GTVADNIAYG KKDASREEII EAAKIAQCDH FIRTLPQGYD 
481:	TIISSENGAL SQGQQQLLTI ARIILANPPV VILDEATSSV DTRTEAHIQK AMETVTENRT 
541:	SFVIAHRLST IENADLILVM KNGDIIEKGT HQELLQAPTL YASLYNSQFQ TT