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3.A.1.135.9
Multidrug exporter, EfrEF.  Mediates efflux of fluorescent substrates and confers resistance towards multiple dyes and drugs including fluoroquinolones (Hürlimann et al. 2016).

Accession Number:Q832K0
Protein Name:ABC transporter, ATP-binding/permease protein
Length:575
Molecular Weight:63400.00
Species:Enterococcus faecalis (strain ATCC 700802 / V583) [226185]
Number of TMSs:5
Substrate drugs, Fluoroquinolones

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKLMKEFIKE NKWIVLATTL TICLQIAGTL GVPKLVGKLI DVGIVSGDQQ VIKTIGIQMF 
61:	LVAFIGTIAA IISSYLSALV AAKFGFQVRG LFFKKFQQFS MKNVDKFGSN SLLTRMTNDV 
121:	DNVQTMIVLF CQLIFPAPII SLFALVMTFS YSVSLAWVTL ASIVFYLVVV YFLMKKGTPL 
181:	SLKIQPKMDR ITTTLREFFT GINMIRAFNN QDFEEQRTNQ TFKNYAERMS KVNQIFAWIT 
241:	PVAFLLMGVV YASILWFGGN LVAVGTLQIG TVTAVIEYTL LTLAYLMIAA MVLVVIPRSV 
301:	ASLNRLQEVL SEEIEISDPH TEATIAYHPE KALICFDHVT FQYTETADPV LENVSFVIPK 
361:	GKTTAIVGAT GAGKSTLVKL LLRINEVTAG TISYSGTDIR SLSQQTIRQV ISYVPQKAFL 
421:	FSGTILSNLL MGNAKATTEE IRTALEISQS SEFIDSLPQG IESFVAQGGS NYSGGQKQRM 
481:	CIARALIKPA DVYIFDDSFS ALDYKTDAAL RAALHAQMSD KTLLIVAQRL STIMNADNII 
541:	VLDEGRIVGQ GTHADLLTTN SYYQDFAKSQ GILPK