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3.A.1.26.7
The putative hydroxyethyl thiazole (biosynthetic precursor of thiamine) porter, ThiW-EcfA1-A2-EcfT (this is a group II ECF transporter which uses a universal energy-coupling module (EcfA1-EcfA2-EcfT) in many firmicutes; Rodionov et al., 2002).

Accession Number:Q839D3
Protein Name:Cobalt transport family protein
Length:265
Molecular Weight:30185.00
Species:enterococcus faecalis [1351]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Hydroxyethyl thiazole

Cross database links:

HEGENOM: HBG510525
RefSeq: NP_814036.1   
Entrez Gene ID: 1199133   
Pfam: PF02361   
KEGG: efa:EF0239   

Gene Ontology

GO:0015087 F:cobalt ion transmembrane transporter activity
GO:0009236 P:cobalamin biosynthetic process
GO:0006824 P:cobalt ion transport

References (1)

[1] “Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.”  Paulsen I.T.et.al.   12663927

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMNKLIFGRY IPGDSFIHRL DPRAKLLASF YFIGIIFLAN NWQSYVLIAA FTAFAISLSK 
61:	ISARFFIRGV RPLLWLILFT VALQTLFTQG GEVYFQWGII SITQFGVTNG LFIFCRFVLI 
121:	IFMSTLLTLT TAPLELSDAI EYLLRPLHVV KFPVHEVSLM LSIALRFVPT LMDETEKIMN 
181:	AQRARGVDFG EGNLLQKMKA IVPLLIPLFV SSFNRAEDLA TAMEARGYQG GEGRTKYRIL 
241:	HWHLRDTIVM FGFVLLTIGL FVLRT