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3.A.1.26.7
The putative hydroxyethyl thiazole (biosynthetic precursor of thiamine) porter, ThiW-EcfA1-A2-EcfT (this is a group II ECF transporter which uses a universal energy-coupling module (EcfA1-EcfA2-EcfT) in many firmicutes; Rodionov et al., 2002).

Accession Number:Q839D4
Protein Name:Cobalt import ATP-binding protein CbiO 2
Length:289
Molecular Weight:32345.00
Species:enterococcus faecalis [1351]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Hydroxyethyl thiazole

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_814035.1   
Entrez Gene ID: 1199132   
Pfam: PF00005    PF12370   
KEGG: efa:EF0238   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0015087 F:cobalt ion transmembrane transporter activity
GO:0006824 P:cobalt ion transport

References (1)

[1] “Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.”  Paulsen I.T.et.al.   12663927

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDIRFKQVDF TYQPNTPFEQ RALFDINLTI QDGSYTAIVG HTGSGKSTLL QHLNALVKPT 
61:	KGQVTIGERV ITPETDNKNL KPIRKKVGIV FQFPEAQLFE ETVERDIAFG PKNFGVSDEE 
121:	AKKLAKKMLD LVGLDEKYLQ HSPFELSGGQ MRRVAIAGVL AMEPEVLVLD EPTAGLDPKG 
181:	RKEMMEMFSR LHKEHNMTIV LVTHLMDDVA NYADHVIVLE KGQIVRAGAP QEVFQETQWL 
241:	KEKQLGVPTA AEFAEKLVAK GFSFEQLPLT ADQLADQLLK KMQEAGEAK