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3.A.1.12.10
The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)).

Accession Number:Q87WH4
Protein Name:OpuC aka PSPTO4576
Length:217
Molecular Weight:22840.00
Species:Pseudomonas syringae pv. tomato GN=PSPTO4576 PE=3 SV=1 [323]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Proline betaine, Carnitine, Acetylcholine, Choline, Glycine betaine

Cross database links:

HEGENOM: HBG592565
RefSeq: NP_794327.1   
Entrez Gene ID: 1186259   
Pfam: PF00528   
BioCyc: PSYR223283:PSPTO_4576-MONOMER   
KEGG: pst:PSPTO_4576   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000.”  Buell C.R.et.al.   12928499

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSFLSAFSHL DWAQVLQLTW QHITLVGIAV TLAIVVGVPL GVLMTRFPAL AGPLQASATV 
61:	LLTVPSIALF GLLLPFYSKF GQGLGPMPAI TAVFLYSLLP IMRNTYLALT GVEPGIREAA 
121:	KGIGMTFGQR LRMVELPIAV PVILAGVRTA VVMNIGVMTI AATIGAGGLG VLILASISRS 
181:	DMSMLIVGAV LVSILAIIAD LLLQWLQRTL TPKGLLK