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3.A.1.12.10
The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)).

Accession Number:Q87WH5
Protein Name:OpuCA aka PSPTO4575
Length:385
Molecular Weight:43107.00
Species:Pseudomonas syringae pv. tomato GN=opuCA PE=3 SV=1 [323]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Proline betaine, Carnitine, Acetylcholine, Choline, Glycine betaine

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_794326.1   
Entrez Gene ID: 1186258   
Pfam: PF00005    PF00571   
BioCyc: PSYR223283:PSPTO_4575-MONOMER   
KEGG: pst:PSPTO_4575   

Gene Ontology

GO:0016020 C:membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0006865 P:amino acid transport

References (1)

[1] “The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000.”  Buell C.R.et.al.   12928499

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIELQNLSKT FQSNGKEVKA VDSVSLTVNE GEICVFLGPS GCGKSTTLKM INRLIMPTSG 
61:	KVLINGEDTT DLDEVTLRRN IGYVIQQIGL FPNMTIEENI VVVPKLLGWD KQRCHDRARE 
121:	LMSMIKLEPK QYLHRYPREL SGGQQQRIGV IRALAADAPL LLMDEPFGAV DPINREMIQN 
181:	EFFEMQRALN KTVIMVSHDI DEAIKLGDKI AIFRGGKLLQ IDHPDTLLAH PADDFVSSFV 
241:	GQDSTLKRLL LVKAEDAADN APSVSPETPV ADALEVMDEN DRRYIVVTDS ENKAMGYVRR 
301:	RDLHRQQGTC AQFLREFNAT AAYDEHLRIL LSRMYEFNRA WLPVLDAENV FLGEVTQESI 
361:	AAYLSSGRSR GMKTSIVSPA EQVAS