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3.A.11.1.2
The single stranded DNA uptake competence transporter, ComEA/ComEC/ComFA (Cvitkovitch 2001; Claverys et al. 2006Claverys et al. 2006).

Accession Number:Q8DQ41
Protein Name:ComEA
Length:216
Molecular Weight:23230.00
Species:Streptococcus pneumoniae (strain ATCC BAA-255 / R6) [171101]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ssDNA

Cross database links:

eggNOG: COG1555
HEGENOM: HBG728721
RefSeq: NP_358450.1   
Entrez Gene ID: 934400   
Pfam: PF00633    PF10531   
BioCyc: SPNE171101:SPR0856-MONOMER   
KEGG: spr:spr0856   

Gene Ontology

GO:0003677 F:DNA binding
GO:0006281 P:DNA repair

References (1)

[1] “Genome of the bacterium Streptococcus pneumoniae strain R6.”  Hoskins J.et.al.   11544234

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEAIIEKIKE YKIIVICTGL GLLVGGFFLL KPAPQTPVKE TNLQAEVAAV SKDLVSEKEV 
61:	NKEEKEEPLE QDLITVDVKG AVKSPGIYDL PVGSRVNDAV QKAGGLTEQA DSKSLNLAQK 
121:	VSDEALVYVP TKGEEAVSQQ TGLGTASSIS KEKKVNLNKA SLEELKQVKG LGGKRAQDII 
181:	DHREANGKFK SVDELKKVSG IGGKTIEKLK DYVTVD